Membrane Proteins
نویسندگان
چکیده
منابع مشابه
Topology of Membrane Proteins
Integral membrane proteins play important roles in living cells. Due to difficulties of experimental techniques, theoretical approaches, i.e., topology prediction methods, are important for structure determination of this class of proteins. Here we show a detailed comparison of transmembrane topology prediction methods. According to this comparison, we conclude that the topology of integral mem...
متن کاملSpecial Section: Membrane Proteins
The function of palmitoylation will depend on the protein that is being considered. Palmitoylation increases the hydrophobicity of proteins and contributes to their membrane association. Progress has been made in our understanding of protein S-palmitoylation as one of a repertoire of dynamic post-translational protein modifications that can control protein trafficking, localization, partitionin...
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You wouldn't call it a long-term relationship, but the interaction between proteins and certain membrane lipids is not just a one-millisecond stand. As Hammond et al. discovered, the proteins remain attached to the lipids longer than researchers expected. The fi ndings explain how these lipids localize their effects. By temporarily hooking up with various proteins, inositol lipids in the plasma...
متن کاملMembrane proteins: shaping up.
Over recent years, much progress has been made in the identification and characterization of factors involved in the biosynthesis of integral membrane proteins of the helix-bundle type. In addition, our knowledge of membrane protein structure and the forces stabilizing helix-helix interactions in a lipid environment is expanding rapidly. However, it is still not clear how a membrane protein fol...
متن کاملSpecial Section: Membrane Proteins
In spite of the functional importance of membrane proteins, information on their structure and organization is lacking due to the paucity of crystal structures. In the absence of a detailed crystallographic database, approaches based on fluorescence spectroscopy have proved useful in elucidating the organization, topology and orientation of membrane proteins. This review is focussed on the appl...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2003
ISSN: 1074-5521
DOI: 10.1016/s1074-5521(03)00006-1